2022 I.ČLTK Prague Open – Women's singles
Jule Niemeier was the defending champion but chose not to participate.
| Women's singles | |
|---|---|
| 2022 I.ČLTK Prague Open | |
| Champion | Maja Chwalińska |
| Runner-up | Ekaterine Gorgodze |
| Score | 7–5, 6–3 |
Maja Chwalińska won the title, defeating Ekaterine Gorgodze in the final, 7–5, 6–3.
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