2022 Atlanta Open – Singles

Alex de Minaur defeated Jenson Brooksby in the final, 6–3, 6–3 to win the singles title at the 2022 Atlanta Open. It was de Minaur's second Atlanta title, the first being in 2019.

Singles
2022 Atlanta Open
Champion Alex de Minaur
Runner-up Jenson Brooksby
Score6–3, 6–3
Draw28
Seeds8

John Isner was the defending champion, but lost in the quarterfinals to Brooksby.

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