2021 Quito Challenger – Singles
Nicolás Jarry was the defending champion but chose not to defend his title.
| Singles | |
|---|---|
| 2021 Quito Challenger | |
| Champion | Facundo Mena |
| Runner-up | Gonzalo Lama |
| Score | 6–4, 6–4 |
Facundo Mena won the title after defeating Gonzalo Lama 6–4, 6–4 in the final.
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