2021 Quito Challenger – Singles

Nicolás Jarry was the defending champion but chose not to defend his title.

Singles
2021 Quito Challenger
Champion Facundo Mena
Runner-up Gonzalo Lama
Score6–4, 6–4

Facundo Mena won the title after defeating Gonzalo Lama 6–4, 6–4 in the final.

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