2021 Abierto Mexicano Telcel – Singles
Alexander Zverev defeated top seed Stefanos Tsitsipas in the final, 6–4, 7–6(7–3) to win the men's singles tennis title at the 2021 Mexican Open.
| Singles | |
|---|---|
| 2021 Abierto Mexicano Telcel | |
| Champion | Alexander Zverev |
| Runner-up | Stefanos Tsitsipas |
| Score | 6–4, 7–6(7–3) |
| Draw | 32 (4 Q / 3 WC ) |
| Seeds | 8 |
Rafael Nadal was the defending champion, but chose not to defend his title.
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