2021–22 Danish Women's 2nd Division

The 2021–22 Danish Women's 2nd Division (Danish: Danmarksturneringens 2. division i kvindefodbold 2021–22) was the first season of the new Danish nation-wide third-tier association football division since its establishment in November 2020 as part of the revised Danmarksturneringen i kvindefodbold's nation-wide league structure. Governed by the Danish FA, the season was launched on 14 August 2021 with two fixtures in the preliminary round (Ballerup-Skovlunde Fodbold vs Østerbro IF and Solrød FC vs BK Fremad Amager) and concluded with the last five matches on 13 November 2021. Østerbro IF, Solrød FC, Ballerup-Skovlunde Fodbold, Fredensborg BK&IF, FC Damsø, JAI Fodbold, IF Lyseng (AGF II), Aarhus 1900, IK Aalborg Freja and Fortuna Hjørring (II) entered as relegated teams from last season's second division, while Allerød FK, BK Fremad Amager, KoldingQ and Vejle BK entered as promoted teams from the last season's third-tier. The eleven first teams, excluding the reserve teams, in the division entered the 2021–22 Danish Women's Cup in the cup tournament's first round proper. The fixtures for the 2021–22 season were announced by the Danish FA's tournament committee and featured a twenty weeks long winter break.

Fortuna Hjørring withdrew their reserve team from the third division shortly before the start of the season. In September 2021, it was announced that KoldingQ would merge and become the new women's department of Kolding IF, which occurred at the end of October 2021. Østerbro IF finished on top of their group following the conclusion of the preliminary round, qualifying for a spot in the 1st Division play-off round against the lowest placed teams of the Danish Women's 1st Division, while JAI Fodbold qualified as the second best team in their group, after Kolding IF (reserves) in first place, due to reserve teams being ineligible for promotion.