2019 Wimbledon Championships – Women's singles

Simona Halep defeated Serena Williams in the final, 6–2, 6–2 to win the ladies' singles tennis title at the 2019 Wimbledon Championships. It was her second major title. The final lasted only 56 minutes, and Halep committed a major-final record of just three unforced errors. She lost only one set during the tournament, to Mihaela Buzărnescu in the second round. Halep became the first Romanian to win a Wimbledon senior singles title. Williams was attempting to equal Margaret Court's all-time record of 24 major singles titles. At 37 years and 291 days, Williams became the oldest major women's singles finalist in the Open Era (a record she herself would pass two months later at the US Open).

Angelique Kerber was the defending champion, but lost in the second round to Lauren Davis. This was the first time in the Open Era that a defending major champion lost to a lucky loser.

This was the first major in which Ashleigh Barty competed as the world No. 1. She retained the top ranking following the tournament despite losing to Alison Riske in the fourth round. Naomi Osaka, Karolína Plíšková, Kiki Bertens and Petra Kvitová were also in contention for the top ranking.

This marked the major main draw debut of future US Open champion Coco Gauff, who at 15 years old became the youngest player to win a main draw Wimbledon singles match since Jennifer Capriati in 1991. In that match, she defeated the oldest player in the draw, five-time Wimbledon champion and 39-year-old Venus Williams. Gauff was also the youngest qualifier in Wimbledon history. She was defeated by Halep in the fourth round.

Karolína Muchová became the first player to reach the quarterfinals of Wimbledon on debut since Li Na in 2006.

This was the first Wimbledon where a final-set tie break rule was introduced. Upon reaching 12–12 in the third set, a classic tie break would be played. No women's singles match required the use of the final-set tie break.