2016 US Open – Mixed doubles
Martina Hingis and Leander Paes were the defending champions, but lost in the second round to CoCo Vandeweghe and Rajeev Ram.
| Mixed doubles | |
|---|---|
| 2016 US Open | |
| Champions | Laura Siegemund Mate Pavić |
| Runners-up | CoCo Vandeweghe Rajeev Ram |
| Score | 6–4, 6–4 |
Laura Siegemund and Mate Pavić won the title, defeating Vandeweghe and Ram in the final, 6–4, 6–4.
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