2016 Italian Open – Women's singles
Serena Williams defeated Madison Keys in the final, 7–6(7–5), 6–3 to win the women's singles tennis title at the 2016 Italian Open. This was Williams's second title in Rome won without dropping a set, and her fourth Italian Open title overall.
| Women's singles | |
|---|---|
| 2016 Italian Open | |
| Champion | Serena Williams |
| Runner-up | Madison Keys |
| Score | 7–6(7–5), 6–3 |
| Draw | 56 (8 Q / 3 WC ) |
| Seeds | 16 |
Maria Sharapova was the reigning champion, but could not defend her title because of her provisional suspension after failing a drug test at the Australian Open.
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