2016 Italian Open – Men's doubles
Pablo Cuevas and David Marrero were the defending champions, but Marrero chose not to participate this year. Cuevas played alongside Marcel Granollers, but lost in the quarterfinals to Vasek Pospisil and Jack Sock.
Bob and Mike Bryan won the title, defeating Pospisil and Sock in the final, 2–6, 6–3, [10–7].
| Men's doubles | |
|---|---|
| 2016 Italian Open | |
| Champions | Bob Bryan Mike Bryan |
| Runners-up | Vasek Pospisil Jack Sock |
| Score | 2–6, 6–3, [10–7] |
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