2015–16 Oklahoma Sooners men's basketball team

The 2015–16 Oklahoma Sooners basketball team represented the University of Oklahoma in the 2015–16 NCAA Division I men's basketball season. The Sooners were led by Lon Kruger in his fifth season. They played their home games at the Lloyd Noble Center in Norman, Oklahoma as a member of the Big 12 Conference. They finished the season 29–8, 12–6 in Big 12 play to finish in third place. They defeated Iowa State in the quarterfinals of the Big 12 tournament to advance to the semifinals where they lost to West Virginia. They received an at-large bid to the NCAA tournament where they defeated Cal State Bakersfield, VCU, Texas A&M, and Oregon to be champions of the West Regional and earn a trip to the Final Four for the fifth time in school history. At the Final Four, they lost in the national semifinal to the eventual champion Villanova by 44 points, the largest margin in Final Four history.