2012 Sony Ericsson Open – Women's singles

Agnieszka Radwańska defeated Maria Sharapova in the final, 7–5, 6–4 to win the women's singles tennis title at the 2012 Miami Open. It was her second Premier Mandatory title and first Miami Masters title. Radwańska did not drop a set during the tournament.

Women's singles
2012 Sony Ericsson Open
Champion Agnieszka Radwańska
Runner-up Maria Sharapova
Score7–5, 6–4
Draw96
Seeds32

Victoria Azarenka was the defending champion, but lost to Marion Bartoli in the quarterfinals, ending Azarenka's 26-match winning streak to start the 2012 season.

This tournament also marked the first WTA Tour main draw appearance of two-time major champion and future world No. 1, Garbiñe Muguruza, where she made the fourth round before losing to Radwańska.

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