2010 Italian Open – Men's doubles
Daniel Nestor and Nenad Zimonjić were the defending champions, but lost in the second round to Pablo Cuevas and Juan Mónaco.
Bob Bryan and Mike Bryan defeated their compatriots John Isner and Sam Querrey in the final. They won 6–2, 6–3.
| Men's doubles | |
|---|---|
| 2010 Italian Open | |
| Champions | Bob Bryan Mike Bryan |
| Runners-up | John Isner Sam Querrey |
| Score | 6–2, 6–3 |
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