2010 Cafés do Brasil Indy 300

The 2010 Cafés do Brasil Indy 300 was an IndyCar motor race held in front of approximately 14,000 people on October 2, 2010, at the Homestead–Miami Speedway in Homestead, Florida. It was the 17th and final showdown of the 2010 IndyCar Series, the final annual edition of the event in the IndyCar Series, and the 15th anniversary of the running of the race (including five years in the Championship Auto Racing Teams (CART) schedule). Chip Ganassi Racing driver Scott Dixon, who started from the second position, won the 200-lap race. Andretti Autosport's Danica Patrick finished second and her teammate Tony Kanaan took third.

Dixon's teammate Dario Franchitti won the pole position by posting the fastest two-lap effort in qualifying. He led the first 42 laps until Ryan Briscoe passed him on lap 43 but retook the position on the next lap. Franchitti led for a total of 128 laps, more than any other driver. He later opted to drive conservatively after his championship rival Will Power crashed in an unsuccessful attempt to lap Ryan Hunter-Reay on the 135th lap. Dixon took the lead on lap 152, and led a total of 47 laps en route to his third victory of the season — the 24th of his career. Patrick, one of five women drivers competing in the event, held off her teammate Kanaan in the final five laps to finish second by 0.0011 seconds.

There were five cautions and an event record-breaking 18 lead changes among seven drivers during the race. The result of the race won Franchitti the third Drivers' Championship of his career and the fourth for Chip Ganassi Racing from finishing eighth. Power's non-finish put him five points behind Franchitti in second place, while Dixon overtook Hélio Castroneves for third, and Briscoe finished the season in fifth place.