2005 US Open – Men's singles
Defending champion Roger Federer defeated Andre Agassi in the final, 6–3, 2–6, 7–6(7–1), 6–1 to win the men's singles tennis title at the 2005 US Open. It was his second US Open title and sixth major title overall. This was Agassi's last appearance in a major final.
| Men's singles | |
|---|---|
| 2005 US Open | |
| Champion | Roger Federer |
| Runner-up | Andre Agassi |
| Score | 6–3, 2–6, 7–6(7–1), 6–1 |
| Draw | 128 |
| Seeds | 32 |
This was the first US Open in which future champions Novak Djokovic, Andy Murray and Stan Wawrinka competed in the main draw. Noteworthy in this tournament was a strong performance by American men, despite 2003 champion and former world No. 1 Andy Roddick losing in the first round. In addition to two-time US Open champion Agassi, wildcard James Blake reached the quarterfinals, upsetting world No. 2 Rafael Nadal in the third round before losing to Agassi. Robby Ginepri, whose run was enhanced by Roddick's early defeat, reached the semifinals and also lost to Agassi.
This tournament marked the last major appearance for former world No. 6 and French Open champion Albert Costa.