2-tert-Butyl-1,1,3,3-tetramethylguanidine

2-*tert*-Butyl-1,1,3,3-tetramethylguanidine
Names
	Preferred IUPAC name N′′-tert-Butyl-N,N,N′,N′-tetramethylguanidine
	Other names BTMG, Barton's base
Identifiers
CAS Number	29166-72-1;
3D model (JSmol)	Interactive image;
ChemSpider	2808676;
ECHA InfoCard	100.157.697
PubChem CID	3571581;
CompTox Dashboard (EPA)	DTXSID10393758 ;
	InChI InChI=1S/C9H21N3/c1-9(2,3)10-8(11(4)5)12(6)7/h1-7H3 Key: YQHJFPFNGVDEDT-UHFFFAOYSA-N;
	SMILES CC(C)(C)N=C(N(C)C)N(C)C;
Properties
Chemical formula	C9H21N3
Molar mass	171.288 g·mol−1
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H314
Precautionary statements	P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

2-tert-Butyl-1,1,3,3-tetramethylguanidine is an organic base, also known as Barton's base. It is named after Nobel Prize-winning British chemist Derek Barton. Barton and his assistants prepared a series of guanidines with steric hindrance in 1982; in this case five alkyl groups: four methyl groups and one tert-butyl group. In 50% water ethanol mixture, the acidity constant (pK_a) of Barton's base is 14. In acetonitrile its pK_a is 24.31.

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