2-Bromoanisole

2-Bromoanisole is an organobromide with the formula BrC6H4OCH3. A colorless liquid, it is one of three isomers of bromoanisole, the others being 3-bromoanisole and 4-bromoanisole. It is a standard coupling partner in metal catalyzed coupling reactions. These reactions include Heck reactions, Buchwald-Hartwig coupling, Suzuki couplings, and Ullmann condensations. The corresponding Grignard reagent readily forms. It is a precursor to o-anisaldehyde.

2-Bromoanisole
Names
Preferred IUPAC name
1-Bromo-2-methoxybenzene
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.008.570
EC Number
  • 209-425-8
PubChem CID
UNII
  • InChI=1S/C7H7BrO/c1-9-7-5-3-2-4-6(7)8/h2-5H,1H3
    Key: HTDQSWDEWGSAMN-UHFFFAOYSA-N
SMILES
  • COC1=CC=CC=C1Br
Properties
Appearance colorless liquid
Melting point 2.5 °C (36.5 °F; 275.6 K)
Boiling point 216 °C (421 °F; 489 K)
Hazards
GHS labelling:
Warning
H411
P273, P391, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.