1999–2000 ANAPROF
The ANAPROF 1999–2000 season was the twelfth season since its establishment. It began on August 1, 1999, and ended on January 30, 2000. 10 teams competed in the league, 9 of which returned from the previous season and 1 of which was promoted from Primera A.
| Season | 1999–2000 |
|---|---|
| Champions | Tauro |
| Relegated | Atlético Municipal Colón |
| Copa Interclubes UNCAF | Tauro Plaza Amador |
| Matches played | 110 |
| Goals scored | 302 (2.75 per match) |
| Top goalscorer | René Mendieta (15) |
| Biggest home win | Sporting '89 6–0 Eurokickers |
| Biggest away win | Chiriquí 1–5 Panamá Viejo Tauro 2–6 Árabe Unido |
| Highest scoring | Tauro 2–6 Árabe Unido |
← 1988 2000–01 → | |
Tauro were crowned champions after defeating Plaza Amador 2-0 in the Rommel Fernández becoming Tauro's fifth title in its history. After clinching this title Tauro earned the Panama 1 spot in the 2001 season of the Copa Interclubes UNCAF while Plaza Amador earned the Panama 2 spot as the runner-up.
Previous to the start of the season there was a championship that went on from April to July amongst the participating teams to determine who would play in the 2000 season of the Copa Interclubes UNCAF; the 1999–2000 Campeonato Apertura. Panamá Viejo was crowned champion on July 2 after defeating Tauro 2-0.