1945 U.S. National Championships – Women's singles

Second-seeded Sarah Palfrey Cooke defeated first-seeded Pauline Betz 3–6, 8–6, 6–4 in the final to win the women's singles tennis title at the 1945 U.S. National Championships.

Women's singles
1945 U.S. National Championships
Champion Sarah Palfrey Cooke
Runner-up Pauline Betz
Score3–6, 8–6, 6–4
Draw32
Seeds8
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