1-Deoxynojirimycin

1-Deoxynojirimycin (DNJ or 1-DNJ), also called duvoglustat or moranolin, is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillus species.

1-Deoxynojirimycin
Names
Preferred IUPAC name
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.119.812
KEGG
PubChem CID
UNII
  • InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
    Key: LXBIFEVIBLOUGU-JGWLITMVSA-N
SMILES
  • C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O
Properties
C6H13NO4
Molar mass 163.173 g·mol−1
Melting point 195 °C (383 °F; 468 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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