1-Aminopropan-2-ol

1-Aminopropan-2-ol is the organic compound with the formula CH3CH(OH)CH2NH2. It is an amino alcohol. The term isopropanolamine may also refer more generally to the additional homologs diisopropanolamine (DIPA) and triisopropanolamine (TIPA).

1-Aminopropan-2-ol
Names
Preferred IUPAC name
1-Aminopropan-2-ol
Other names
1-Amino-2-propanol
Isopropanolamine
MIPA; Threamine
Identifiers
  • Compounds
  • (+/−)-1-Aminopropan-2-ol
  • (R): (−)-1-Aminopropan-2-ol
  • (S): (+)-1-Aminopropan-2-ol
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.001.057
EC Number
  • 201-162-7
  • (R): 220-532-9
  • (S): 220-533-4
KEGG
PubChem CID
UNII
  • InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3 Y
    Key: HXKKHQJGJAFBHI-UHFFFAOYSA-N Y
  • (R): InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3/t3-/m1/s1
    Key: HXKKHQJGJAFBHI-GSVOUGTGSA-N
  • (S): InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3/t3-/m0/s1
    Key: HXKKHQJGJAFBHI-VKHMYHEASA-N
SMILES
  • OC(C)CN
  • (R): O[C@H](C)CN
  • (S): O[C@@H](C)CN
Properties
C3H9NO
Molar mass 75.111 g·mol−1
Appearance liquid
Odor ammonia-like
Density 0.973 g/mL (18 °C)
Melting point 1.74 °C (35.13 °F; 274.89 K)
Boiling point 159.46 °C (319.03 °F; 432.61 K)
soluble
Solubility soluble in alcohol, ether, acetone, benzene, CCl4
Refractive index (nD)
1.4479
Hazards
NFPA 704 (fire diamond)
2
2
0
Flash point 77 °C (171 °F; 350 K)
374 °C (705 °F; 647 K)
Lethal dose or concentration (LD, LC):
LD50 (median dose)
4.26 g/kg (rat, oral)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1-Aminopropan-2-ol is chiral. It can be prepared by the addition of aqueous ammonia to propylene oxide.

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